Po-boys · Uptown New Orleans

Domilise's Po‑Boy & Bar

Oyster and fried shrimp po-boys from a family-run Uptown spot, over 100 years and counting.

Reviews

What people say.

4.5

1,769 reviews on Google

Read them
“Best oyster po boy in New Orleans. Hands down.”
Russ M. · Google review

Visit

On Annunciation Street.

Street map around 5240 Annunciation St, New Orleans, LA 70115 Get directions

Address

5240 Annunciation St, New Orleans, LA 70115

Hours

Mon – Wed11 AM – 3 PM
Thursday11 AM – 5 PM
Fri – Sat11 AM – 7 PM
SundayClosed

Hours as published, October 2026.